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A selective nerve root block is an injection of local anesthetic and steroid into the area where the nerve root exits the spinal column. A nerve root block usually is performed for pain in the arm or leg that follows the path of a single nerve (i.e. sciatica). A selective nerve root block may be diagnostic and/or therapeutic. Therapeutic injections are intended to provide long-term pain relief. Most patients require more than one injection.  If you receive sufficient relief from the injection, the nerve root block can be repeated if your pain returns.